Medical Oncology
The Medical Oncology Clinical Trials Team conducts clinical trials of new drugs for patients with cancer.
IOS-1002-201 - administered alone and in combination with a PD-1 monoclonal antibody in advanced solid tumors
A Phase 1a/1b, first-in-human, open-label, non-randomized, multicenter, dose-escalation and cohort expansion study to evaluate the safety, tolerability, efficacy, immunogenicity, pharmacokinetics, and pharmacodynamics of IOS-1002 administered alone and in combination with a PD-1 monoclonal antibody in advanced solid tumors.
Keynote-B15
The trial is testing a potential new treatment for Muscle-invasive Bladder Cancer.
lidERA - Trialing a new oral hormone receptor blocker in estrogen receptor positive breast cancer
Evaluating the efficacy and safety of post surgical Giredestrant compared with doctors choice of endocrine therapy (Tamoxifen, Anastrozole, Letrozole or Exemestane) in patients with estrogen receptor−positive, HER2-negative early breast cancer.
Medical Oncology Trials
The Medical Oncology Clinical Research team, based within the Mater Cancer Care Centre, currently has 22 actively recruiting trials.
PARAGON-II
This trial is for people with gynaecological cancers whose tumours are potentially treatable with endocrine treatment.
RC-48
The trial is testing a potential new treatment called disitamab vedotin for Muscle-invasive Bladder Cancer.
TROPION-Lung10
TROPION-Lung10: First-line Treatment of Participants With Locally-advanced or Metastatic Non-squamous NSCLC With High PD-L1 Expression
VIKTORIA-1
The purpose of this study is to evaluate the safety and effectiveness of gedatolisib at treating your cancer when combined with other cancer drugs, compared to the standard of care for people with breast cancer.
XL092-304
The research project is testing a potential new treatment for nccRCC, called XL092 in a combination with nivolumab.
Zn-c3 - A potential new treatment for advanced ovarian, peritoneal or fallopian tube cancer
A potential new treatment for advanced ovarian, peritoneal or fallopian tube cancer.