Mater Inflammatory Bowel Disease Biobank

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gut believed to have a multi-factorial aetiology. The Mater Inflammatory Bowel Disease Biobank was conceived to collect biospecimens from patients and healthy controls undergoing endoscopy to help elucidate the complex causes of IBD, the progression of disease over time, the various phenotypic manifestations and explore the complex interaction between the immune system and the gut ecosystem.

The Biobank houses matched tissue biopsy specimens for histologic analysis, RNA expression analysis and DNA for mucosal microbiome composition analysis as well as serum samples, germline DNA from whole blood and stool samples for microbial analysis. This is paired with a clinical database for IBD patients which captures disease behaviour, disease activity (at each site), medications and other clinical data.

The Biobank collects the following samples:

• Genomic DNA from whole blood
• Serum samples
• RNA from biopsy specimens (ileum, ascending colon, and sigmoid colon)
• DNA from biopsy specimens (ileum, ascending colon, and sigmoid colon)
• Formalin fixed biopsy samples (ileum, ascending colon, and sigmoid colon)
• Stool samples
  
  

Contact Us

Donors or researchers interested in further information about the Mater Mater Inflammatory Bowel Disease Biobank can contact:
Associate Professor Jakob Begun, Inflammatory Bowel Diseases Research Group Leader, Mater Research